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Effect of Procedure Sequence on Hypoxemia During Painless Bidirectional Endoscopy in High-Risk Patients: A Randomized Controlled Trial

Effect of Procedure Sequence on Hypoxemia During Painless Bidirectional Endoscopy in High-Risk Patients: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110335
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-10-15
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxemia

Interventions

Experimental Group (undergoing colonoscopy first, followed by gastroscopy):For patients predicted to be at high risk of hypoxemia during painless endoscopy according to the risk prediction model, the
Control Group (undergoing gastroscopy first, followed by colonoscopy):The procedure is conducted in the order of gastroscopy first, followed by colonoscopy.

Sponsors

The Second Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18–75 years; 2.ASA physical status <= III and scheduled to undergo painless bidirectional gastrointestinal endoscopy; 3.Provided informed consent and willing to participate in the study and share relevant data; 4.Identified as high-risk for hypoxemia by the predictive model for hypoxemia during painless gastrointestinal endoscopy.

Exclusion criteria

Exclusion criteria: 1.Goiter or history of thyroid surgery; 2.History of other neck surgeries; 3.Severe cardiovascular, cerebrovascular, or pulmonary diseases; 4.Severe renal or hepatic dysfunction; 5.Neurocognitive or psychiatric disorders; 6.Epilepsy or seizure episodes; 7.Preoperative use of sedatives or analgesics; 8.Pregnant or breastfeeding individuals; 9.Allergy to anesthetic agents; 10.Refusal or inability to comply with the study protocol

Design outcomes

Primary

MeasureTime frame
Pulse Oximetry Oxygen Saturation (SpO?) < 92%;

Secondary

MeasureTime frame
Incidence of Hypoxemia (SpO2 <= 90%);Adverse Events Occurring During and After the Examination;

Countries

China

Contacts

Public ContactJiang Zhu

The Second Affiliated Hospital of Soochow University

zhujiangsz@126.com+86 139 6215 3438

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026