Tumors of the chest and upper abdomen
Conditions
Interventions
Chest and upper abdominal tumor group:Carry out stereotactic radiotherapy guided by the VSM-DIBH technology
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Tumor types: liver metastases, pancreatic cancer, and other upper abdominal tumors (near the diaphragm); 2. Respiratory control ability: the patient can independently perform deep inspiration breath-hold (DIBH) maneuvers, with a breath-hold time of >=20 seconds and respiratory amplitude fluctuation <=3mm (monitored via the VSM system); 3. Anatomical stability: target volume <=5cm, without significant pleural or abdominal effusion or diaphragm adhesion; 4. The investigator judges, based on the subject's medical history, physical examination, and vital signs, that their general health status is suitable.
Exclusion criteria
Exclusion criteria: 1. Respiratory dysfunction: Acute stage of COPD, severe impairment of lung function (FEV1 < 50% of predicted value) or inability to perform breath-holding training; 2. Positional restrictions: Unable to lie flat or maintain a fixed position (such as severe spinal deformity); 3. Suffering from uncontrollable comorbid diseases, including but not limited to symptomatic congestive heart failure, uncontrolled hypertension, unstable angina pectoris, arrhythmia, active peptic ulcer or bleeding disorders; 4. Patients with patent foramen ovale; 5. Patients unable to cooperate with continuous follow-up.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Acute toxic reaction;Progression-free survival, PFS; | — |
Primary
| Measure | Time frame |
|---|---|
| 3-month effective rate; | — |
Countries
China
Contacts
Public ContactWang Hao
Peking University Third Hospital
Outcome results
None listed