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Exploration of the application of alfentanil in anesthesia induction for pediatric day surgery:a single-center, prospective, double-blind, randomized controlled study

Exploration of the application of alfentanil in anesthesia induction for pediatric day surgery:a single-center, prospective, double-blind, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110329
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric ambulatory surgery

Interventions

Fentanyl-Trachea tube Group:Use fentanyl as an opioid during induction,and use endotracheal intubation in airway management
Alfentanil-Laryngeal Mask Airway Group:Use alfentanil as an opioid during induction,and use Laryngeal Mask Airway in airway management
Fentanyl-Laryngeal Mask Airway Group:Use fentanyl as an opioid during induction,and use Laryngeal Mask Airway in airway management
Alfentanil-Trachea tube Group:Use alfentanil as an opioid during induction,and use endotracheal intubation in airway management

Sponsors

WeiHai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1.Pediatric patients under 18 years of age, ASA physical status I-II, scheduled for daytime surgery under general anesthesia. 2.Pediatric patients undergoing daytime surgery without severe comorbidities or congenital diseases. 3.Patients who can cooperate with communication and complete follow-up indicators. 4.Patients who sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.History of major surgical procedures, such as cardiac surgery and craniotomy. 2.Contraindications to alfentanil or other investigational drugs. 3.Allergy to investigational drugs; 4.Mental illness or intellectual developmental disorders that may affect the study or the patient's ability to cooperate with follow-up. 5.Other contraindications to general anesthesia;

Design outcomes

Primary

MeasureTime frame
The pediatric patient exhibited agitation and delirium in the post-anesthesia recovery room.;

Secondary

MeasureTime frame
Patient anesthesia recovery time and duration of stay in the Post-anesthesia Care Unit (PACU), including adverse reactions such as nausea and vomiting;Hypoxemia occurrence in the Post-anesthesia Care Unit (PACU);Parents' Satisfaction Evaluation of This Hospitalization;Laryngeal Mask Airway (LMA) and Endotracheal Intubation Insertion Criteria;The Systolic blood pressure?Diastolic blood pressure?Mean arterial pressure and Heart rate of the patient Upon entering the operating room?After induction of anesthesia;Pain status in the Post-anesthesia Care Unit;

Countries

China

Contacts

Public ContactWang Xiaodong

WeiHai Municipal Hospital

wxd1982819@126.com+86 631 528 7057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026