osteosarcoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pathological diagnosis of common osteosarcoma; 2. The Ennecking staging of osteosarcoma is stage II and III; 3. Not treated with chemotherapy, other tumor related drugs, or surgery; 4. Those who agree to receive neoadjuvant chemotherapy, surgical treatment, and postoperative chemotherapy; 5. Age range from 0 to 75 years old, gender not limited; 6. Expected survival period is greater than 12 months.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of other malignant tumors; 2. Those who do not receive treatment and undergo regular check ups during follow-up; 3. Those who have poor compliance and refuse to sign informed consent forms; 4. Individuals with severe coagulation dysfunction; 5. Patients with severe cardiovascular and pulmonary diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of the Survivor gene and protein in circulating tumor cells; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number and classification of circulating tumor cells;Patient's survival status and survival time; | — |
Countries
China
Contacts
Department of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Guangxi Medical University