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Expression of Survivi gene in circulating tumor cells (CTCs) of osteosarcoma

Expression of Survivi gene in circulating tumor cells (CTCs) of osteosarcoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110328
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteosarcoma

Interventions

Osteosarcoma:None

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 75 Years

Inclusion criteria

Inclusion criteria: 1. Pathological diagnosis of common osteosarcoma; 2. The Ennecking staging of osteosarcoma is stage II and III; 3. Not treated with chemotherapy, other tumor related drugs, or surgery; 4. Those who agree to receive neoadjuvant chemotherapy, surgical treatment, and postoperative chemotherapy; 5. Age range from 0 to 75 years old, gender not limited; 6. Expected survival period is greater than 12 months.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of other malignant tumors; 2. Those who do not receive treatment and undergo regular check ups during follow-up; 3. Those who have poor compliance and refuse to sign informed consent forms; 4. Individuals with severe coagulation dysfunction; 5. Patients with severe cardiovascular and pulmonary diseases.

Design outcomes

Primary

MeasureTime frame
Expression of the Survivor gene and protein in circulating tumor cells;

Secondary

MeasureTime frame
The number and classification of circulating tumor cells;Patient's survival status and survival time;

Countries

China

Contacts

Public ContactYun Liu

Department of Spinal and Orthopedic Surgery, the First Affiliated Hospital of Guangxi Medical University

liuyun@gxmu.edu.cn+86 134 8119 5445

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026