Postoperative pain
Conditions
Interventions
Trial group (Group B):Group B patients received either 15 mL of 0.886% bupivacaine liposome under ultrasound-guided supraclavicular approach for brachial plexus block, or 30 mL of 0.33% ropivacaine hy
Control group (L group):Group L patients received 15 mL of 0.33% ropivacaine hydrochloride for ultrasound-guided supraclavicular brachial plexus block, and 30 mL of 0.33% ropivacaine hydrochloride for
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Before the trial, fully understand the nature, significance, and potential benefits of the trial, as well as the possible inconveniences and potential dangers Understand the research procedures and voluntarily sign the informed consent form in writing. 2.Patients scheduled for elective intramedullary nailing of forearm fractures; 3.No gender restrictions, aged 18-65 years; 4.BMI19.0~26.0kg/m^2; 5.The ASA (American Society of Anesthesiologists) physical status classification is I to II.
Exclusion criteria
Exclusion criteria: 1.The patient refuses to undergo brachial plexus block; 2.The patient has a history of specific allergic diseases (asthma, urticaria, eczema, etc.) or is known to be allergic bupivacaine; 3.The patient has a history of surgery on the neck or supraclavicular fossa on the surgical side; there is damage or infection in theillary and supraclavicular puncture areas; 4.The patient has abnormal coagulation function; 5.The patient has a history of chronic neuropathic pain. 6.Chronic opioid use (e.g., morphine sulfate extended-release tablets, oxycodone hydrochloride extended-release tablets, fentanyl transmal patches, etc.); 7.Surgical limb nerve function defect; 8.The patient has a history of mental illness; 9.The patient is concurrently enrolled in another clinical trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting NRS score;Duration of sensory and motor block;Incidence of adverse events of local anesthetic in patients;Postoperative opioid consumption and pain satisfaction;Incidence of adverse events of nerve block manipulation in patients;Incidence of postoperative nausea and vomiting and use of antiemetics; | — |
Countries
China
Contacts
Public ContactHuang Jian
The first affiliated hostipal of nanchang university
Outcome results
None listed