Motion Sickness
Conditions
Interventions
Trial group:taVNS
Sponsors
The Second Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Willing to sign the informed consent form; 2) Aged between 18 and 65, regardless of gender.
Exclusion criteria
Exclusion criteria: 1) Taking antipyretic analgesics (such as paracetamol, DayQuil/NyQuil, Tylenol, etc.), sedative-hypnotics (such as diazepam, barbiturates, chlorpromazine, etc.), or anti-motion sickness drugs (such as scopolamine, diphenhydramine, dimenhydrinate, meclizine, etc.) within 24 hours before the trial and during the training period; 2) Exhibiting significant symptoms of upper respiratory tract infection (axillary temperature >37.5°C accompanied by coughing, runny nose, sore throat, etc.), acute gastroenteritis, or food poisoning (vomiting or diarrhea) within 5 days before the trial and during the training period; 3) A history of autoimmune diseases affecting gastrointestinal motility (such as systemic sclerosis, dermatomyositis), cardiovascular and cerebrovascular diseases (hypertension, coronary heart disease, cerebral hemorrhage, cerebrovascular embolism), digestive system diseases (gastroduodenal ulcers, gastroesophageal reflux disease, digestive system tumors), neuropsychiatric disorders (trigeminal neuralgia, migraine, depression, schizophrenia), or vestibular system disorders (Meniere's disease, vestibular neuritis, benign paroxysmal positional vertigo); 4) Smoking >= 5 cigarettes per day; 5) Inability to abstain from excessive alcohol consumption during the study period (equivalent to >= 40g of ethanol per day for males); 6) Allergy to metal electrodes; 7) Pregnancy or breastfeeding; 8) Any other conditions deemed unsuitable for participation by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total tolerable rotation time;Heart Rate Variability;Serum hormone variations; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motion Sickness Symptom Ratings;Gastric slow wave variability; | — |
Countries
China
Contacts
Public ContactBeifang Ning
The Second Affiliated Hospital of Naval Medical University
Outcome results
None listed