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The fate determining mechanism and targeted precise regulation of Gli1+stem cells involved in wound repair of the motor system

The fate determining mechanism and targeted precise regulation of Gli1+stem cells involved in wound repair of the motor system

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110315
Enrollment
Unknown
Registered
2025-10-11
Start date
2025-10-11
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis,Lumbar disc herniation

Interventions

Control group:None
Lumbar intervertebral disc protrusion group:None

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Subjects who voluntarily participate in this trial and sign the informed consent; 2.Patients who commit to comply with the research procedures and cooperate with the implementation of the entire research process; 3.Clear diagnosis of knee osteoarthritis and lumbar disc herniation and meeting surgical indications; 4.Complete case information;

Exclusion criteria

Exclusion criteria: 1.Pregnant patients; 2.Patients with severe hypertension, heart disease, diabetes, abnormal coagulation function and other serious conditions that are not suitable for surgical treatment; 3.Diagnosed with rheumatic diseases such as rheumatoid arthritis and ankylosing spondylitis within 5 years; Patients are excluded if any of the above conditions are met.

Design outcomes

Primary

MeasureTime frame
Clinical manifestations and imaging examination results;

Countries

China

Contacts

Public ContactWei Yulong

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

yulongwei@hust.edu.cn+86 27 8535 1627

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026