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Effect of Lidocaine on the Effective Dose of Remifentanil to Suppress Tracheal Intubation Response in Elderly Patients

Effect of Lidocaine on the Effective Dose of Remifentanil to Suppress Tracheal Intubation Response in Elderly Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110314
Enrollment
Unknown
Registered
2025-10-11
Start date
2025-11-15
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological diseases

Interventions

Sponsors

Women and Children’s Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Female patients scheduled for gynecological surgery under general anesthesia with endotracheal intubation; 2. Age >= 65 years; 3. ASA class I~III; 4. BMI 19~30 kg/m^2; 5. Mallampati class I~II.

Exclusion criteria

Exclusion criteria: 1.Combined arrhythmia, stroke, or cerebral infarction; 2.Combined difficult airway; 3.Preoperative blood pressure greater than 180/110 mmHg, or individuals at significant risk of elevated intraocular or intracranial pressure; 4.Patients with a history of hyperthyroidism; 5.Neurological and mental disorders; 6.Individuals allergic to the study drug.

Design outcomes

Primary

MeasureTime frame
The incidence rate of tracheal intubation reactions;

Secondary

MeasureTime frame
Hemodynamic Parameters;

Countries

China

Contacts

Public ContactShen Yanping

Ningbo University Affiliated Women's and Children's Hospital

y218180460@zju.edu.cn+86 572 391 5413

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026