Breast Cancer
Conditions
Interventions
Liposomal Bupivacaine Group:Dilute 20 ml of 1.3% liposomal bupivacaine to 30 ml for Pecs? Block
Ropivacaine group:0.25% ropivacaine 30ml for Pecs? Block
Sponsors
Tianjin Cancer Hospital (Tianjin Medical University Cancer Hospital)
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age: 20 to 65 years old; 2. American Society of Anesthesiologists (ASA) Grade I and II; 3. Patients who have been diagnosed with breast cancer and are scheduled to undergo endoscopic radical mastectomy and immediate breast reconstruction.
Exclusion criteria
Exclusion criteria: 1. Has a history of neurological diseases, mental disorders, heart and lung diseases, and liver and kidney function impairments; 2. Allergy to local anesthetics or liposome components; 3. Abnormal coagulation function; 4. Infection at the puncture site; 5. Long-term oral analgesics; 6. Patients with concurrent other cancers or distant metastases; 7. Postoperative pain assessment or follow-up after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting VAS score;Excercise VAS score;The incidence rate of chronic pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total consumption of opioid drugs;The effective pressing times of the analgesia pump;Number of rescue analgesia times;Adverse reactions related to opioid drugs;The quality of the patient's recovery; | — |
Countries
China
Contacts
Public ContactDeng Chengqi
Tianjin Cancer Hospital (Tianjin Medical University Cancer Hospital)
Outcome results
None listed