acute respiratory failure
Conditions
Interventions
control group (HAMILTON-T1):Imported emergency transport ventilator
Intervention group (TV80):domestically produced high-performance emergency transport ventilator
Sponsors
Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Aged >= 18 years and < 80 years. (2) Patients receiving invasive mechanical ventilation. (3) Patients requiring intra-hospital transport or inter-hospital transfer. (4) Patients whose legal representatives have provided written informed consent for participation in the trial.
Exclusion criteria
Exclusion criteria: (1) Subjects with shock or hemodynamic instability that has not been treated (2) Subjects receiving high-dose vasopressor support (equivalent norepinephrine dose > 1µg/kg/min) (3) Patients receiving ECMO support (4) Subjects with hemoglobin < 6g/dL (5) Subjects with cardiac arrest without resuscitation treatment (6) Patients who are moribund or discharged due to deteriorating condition (7) Patients with bullae, pneumothorax without closed thoracic drainage, especially tension pneumothorax (8) Massive hemoptysis, and respiratory failure caused by massive hemoptysis or severe aspiration (9) Pregnant and lactating women (10) Patients with mental illness (11) Subjects whose legal representatives have not provided informed consent (12) Patients without access to trial ventilators during the trial, including when trial ventilators are in use or malfunctioning (13) Expected transport duration exceeding 1 hour or combined transport scenarios (helicopter combined with ambulance)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in PaO2/FiO2 before and after transferring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Variation in heart rate before and after transferring;Variation in SPO2 before and after transferring;Variation inPaCO2 before and after transferring;Variation in tidal volume before and after transferring;Preparing time for transferring;Difference in pH before and after transferring;Variation in mean arterial pressure and after transferring;Variation in FiO2 before and after transferring; | — |
Countries
China
Contacts
Public ContactShanxiang Xu
Second Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed