Skip to content

Clinical Study on Ozone Autologous Blood Reinfusion versus Dexamethasone Intravenous Drip in the Treatment of Acute Herpes Zoster

Clinical Study on Ozone Autologous Blood Reinfusion versus Dexamethasone Intravenous Drip in the Treatment of Acute Herpes Zoster

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110265
Enrollment
Unknown
Registered
2025-10-11
Start date
2023-10-12
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes zoser neuralgia

Interventions

Group A:Group A received intravenous infusion of 5 mg dexamethasone injection daily for 5 consecutive days after admission.
Group B:Group B underwent ozone autohemotherapy once daily for 5 consecutive days after admission, with the specific method as follows: Strictly adhering to aseptic techniques, the median cubital vein

Sponsors

Nanjing Medical University Fourth Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. The subject voluntarily signs the informed consent for this clinical observation. 2. Age is greater than or equal to 50 years and less than or equal to 90 years, gender-neutral. 3. The time of rash appearance does not exceed 3 days. 4. The numerical pain rating scale (Numerical Rating Scale, NRS) is not less than 4 points.

Exclusion criteria

Exclusion criteria: 1. Those who do not meet the inclusion criteria, or those determined by a physician to be unsuitable for participating in this trial. 2. Allergic to ozone, dexamethasone, or acyclovir. 3. Coagulation dysfunction. 4. Suffering from malignant tumors. 5. Moderate to severe anemia. 6. Currently using immunosuppressants. 7. Presence of severe respiratory, circulatory system, or hepatic and renal insufficiency.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale score;

Secondary

MeasureTime frame
C-reactive protein;Monocyte;Lymphocyte;Monocyte ratio;Lymphocyte ratio;Hemoglobin;Erythrocyte Sedimentation Rate ;Serum albumin;Serum globulin;Interleukin-6;Blood glucose in fasting serum;Daily dosage of analgesics;

Countries

China

Contacts

Public ContactCheng Zhuqiang

Nanjing Medical University Fourth Affiliated Hospital

zqcheng123@126.com+86 159 5181 2689

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026