obesity
Conditions
Interventions
Control group:On the basis of the original diet and exercise regime, subjects will be given placebos with an identical appearance (e.g., olive oil capsules).
Intervention group:On the basis of the original diet and exercise regimen, the intervention group will supplement with Omega-3 (EPA + DHA >=4g) daily and restrict Omega-
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-65 years, with BMI >=28 kg/m² (meeting the obesity standard); 2.Stable body weight (weight change < 5% in the past 3 months); 3.No severe liver or kidney dysfunction, and no history of taking ?-3 supplements or fish oil drugs;
Exclusion criteria
Exclusion criteria: 1.Complicated with endocrine-related obesity such as Cushing's syndrome and thyroid diseases; 2.Having taken anti-inflammatory drugs, lipid-lowering drugs, or Omega-3/6 supplements in the past 3 months; 3.Being pregnant or lactating;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weigh;body fat percentage; | — |
Secondary
| Measure | Time frame |
|---|---|
| intestinal flora;Omega-3/6 ratio;lipid metabolism indices;urinary metabolomics;Homeostasis Model Assessment of Insulin Resistance;inflammatory markers; | — |
Countries
China
Contacts
Public ContactYangjuhong
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed