Patients Undergoing Gynecologic Laparoscopic Surgery
Conditions
Interventions
Experimental group (The Oliceridine Group):The experimental group received 3 mg of oliceridine for anesthetic induction.
Control group (The Sufentanil Group):The control group received 0.4 µg/kg of sufentanil for anesthetic induction.
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
Female
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age < 80 years; 2.Scheduled for gynecologic laparoscopic surgery; 3. American Society of Anesthesiologists (ASA) physical status class I-III.
Exclusion criteria
Exclusion criteria: 1.Dyspnea or tracheal compression; 2.Obstructive sleep apnea syndrome (OSAS); 3. History of neurological disorders such as stroke or epilepsy; 4. Severe impairment of hepatic or renal function, heart failure, malignant tumors, etc.; 5.Long-term use of analgesic medications; 6.Mental disorders that would prevent cooperation with the study; 7.Known allergy to any drug used in this study; 8. Pregnancy, lactation, or intended pregnancy; 9.Current participation in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative nausea and vomiting (PONV) within 48 hours after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of PONV;The number of rescue antiemetics required;Postoperative patient satisfaction score;Time of tracheal extubation;PACU duration and postoperative hospital stay;Frequency of rescue pain medication;Hemodynamic event; | — |
Countries
China
Contacts
Public ContactLiu Feng
Shanghai East Hospital
Outcome results
None listed