Postoperative analgesia for thoracic patients
Conditions
Interventions
Bupivacaine liposome:Bupivacaine liposome
Bupivacaine hydrochloride:Bupivacaine hydrochloride
Control group:Conventional pain pump therapy
Sponsors
Kunshan First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Selective unilateral thoracoscopic lung surgery; 2) 18 to 80 years old; 3) The American Society of Anesthesiologists (ASA) grades I-III.
Exclusion criteria
Exclusion criteria: 1) Contraindications for the use of local anesthetics: infection at the puncture site, allergy to local anesthetics, coagulation dysfunction, or risk of bleeding; 2) There are sensory abnormalities in the surgical area of the chest wall; 3) Liver and kidney dysfunction. Abnormal liver function: ALT>50U/L or AST>40U/L, or TBIL >= 19 × µ mol/L; Abnormal renal function: Cr>112 µ mol/L or BUN>7.1mmol/L or received dialysis treatment within 28 days before surgery; 4) Pregnancy, lactation, potential pregnancy, and planned pregnancy; 5) Preoperative use of opioid analgesics or history of chronic pain or opioid abuse; 6) Patients who refuse to participate;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the pain score curve 25~72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS Score; | — |
Countries
CHINA
Contacts
Public ContactHang Lihua
Kunshan First People's Hospital
Outcome results
None listed