Rheumatoid arthritis
Conditions
Interventions
Normal group:None
Non refractory rheumatoid arthritis group:None
Refractory rheumatoid arthritis group:None
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meets the Western diagnostic criteria for rheumatoid arthritis; 2. Meet the diagnostic criteria for refractory rheumatoid arthritis set by the European Union Against Rheumatism; 3. Meet the criteria for active rheumatoid arthritis, i.e. DAS28>3.2; 4. Age >= 18 years old; 5. The subjects agree to join this study and sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and kidney dysfunction; 2. Patients with severe primary diseases of cardiovascular, pulmonary, renal, endocrine, and hematopoietic systems; 3. Have a history of hepatitis B, hepatitis C, tuberculosis, AIDS, acquired immunodeficiency syndrome (AIDS) or malignant tumor; 4. Patients with combined inflammatory arthritis diseases such as psoriatic arthritis, ankylosing spondylitis, and gouty arthritis; 5. Individuals with mental illnesses who lack self-awareness and are unable to express themselves accurately; 6. Pregnant, lactating women or those preparing for pregnancy; 7. Patients who are currently participating or have participated in other clinical trials within the past month; 8. Researchers have determined that patients have poor compliance and are unable to complete the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biomarkers; | — |
Secondary
| Measure | Time frame |
|---|---|
| erythrocyte sedimentation rate;C-reactive protein;rheumatoid factor;Rheumatoid antibodies; | — |
Countries
China
Contacts
Public ContactWei Liu
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed