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Randomized controlled study of three intersegmental planar display methods in 3D-CTBA-guided precision segmentectomy in patients with emphysema for early non-small cell lung cancer

Randomized controlled study of three intersegmental planar display methods in 3D-CTBA-guided precision segmentectomy in patients with emphysema for early non-small cell lung cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110222
Enrollment
Unknown
Registered
2025-10-10
Start date
2024-05-20
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early non-small cell lung cancer

Interventions

The modified swelling and collapse group:After accurate treatment of the target segment bronchus, target segment pulmonary artery, and target segment pulmonary vein, the anesthesiologist was instructe
The indocyanine green fluorescence imaging group:After treatment of the target pulmonary artery, vein and bronchus, injection of indocyanine green (ICG) is injected under the peripheral vein. ICG is c
The methylene blue staining group:Methylene blue staining is based on the principle of endobronchial staining. After cutting off the target segment arteriovenous and bronchus, methylene blue solution

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient's lung CT imaging indicates pulmonary emphysema; 2. Meets the NCCN lung cancer treatment guidelines for segmental lung resection; 3. Patient age between 18-75 years; 4. Good lung function, FEV1 >= 1L and at least 70% of the predicted value; 5. No history of ipsilateral thoracotomy; 6. No preoperative chemotherapy, radiotherapy, targeted therapy, or immunotherapy; 7. Preoperative clinical evaluation indicates cardiopulmonary and liver and kidney function can tolerate surgery; 8. American Society of Anesthesiologists (ASA) score I-III; 9. Patient has provided informed consent.

Exclusion criteria

Exclusion criteria: 1. Individuals allergic to indocyanine green or methylene blue, or with abnormal liver function; 2. History of other malignancies within the past 5 years; 3. Suffering from severe mental illness; 4. Pregnant or breastfeeding women; 5. History of cerebral infarction or cerebral hemorrhage within the past 6 months; 6. History of serious heart disease, heart failure, myocardial infarction, or angina attack within the past 6 months; 7. Deemed unsuitable for participation in the trial by the investigator.

Design outcomes

Primary

MeasureTime frame
Intersegmental plane appearance time;Operation time;

Secondary

MeasureTime frame
Intraoperative blood loss;Postoperative drainage volume;Postoperative complications;Hospital stay;Intraoperative complications;Drainage tube removal time ;

Countries

China

Contacts

Public ContactChen Shuchen

Fujian Medical University Union Hospital

cscdoctor@163.com+86 139 5020 7801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026