Delayed recovery after general anesthesia, postoperative delirium, cognitive impairment, postoperative sleep disorders, etc.
Conditions
Interventions
Experimental group:A general anesthetic regimen with remimazolam as the main one is used
Control group:Use a total anesthesia scheme mainly based on propofol.
Sponsors
Hebei Medical University Third Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age 60~85 years old; 2. Preoperative PSQI < 7 points; 3. ASA Level I-III; 4. Body mass index BMI<=35kg/m^2; 5. Gender is not limited; 6. Patients undergoing downward spine surgery under general anesthesia; 7. Patients who are proposed to undergo experimental protocol A/B: A. The experimental group uses remimazolam, sufentanil, and cis-atracurium for induction anesthesia; Anesthesia is maintained with remimazolam and remifentanil. Sevoflurane is applied as necessary during induction and maintenance. B. The control group was given propofol, sufentanil, and cis-atracurium for induction anesthesia. Maintain anesthesia with propofol and remifentanil. Sevoflurane application if necessary during induction and maintenance;
Exclusion criteria
Exclusion criteria: 1.For individuals allergic to research drugs; 2.Recently abused sleep aid drugs; 3.Patients with communication barriers; 4.Severe liver and kidney dysfunction; 5.Merge other injuries that require simultaneous surgery; 6.Emergency operation; 7.Patients transferred to ICU after surgery; 8.Patients who did not use pain pumps after surgery;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of awakening; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic information;Sleep quality;Adverse event;Anesthesia surgery information; | — |
Countries
China
Contacts
Public ContactZhao Shuang
Hebei Medical University Third Hospital
Outcome results
None listed