Multiple Sclerosis
Conditions
Interventions
Observational group:Patients with suspected MS, CIS, or RIS
Sponsors
Yan'an University Xianyang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with suspected central nervous system disease were enrolled and later classified following the diagnostic procedure upon confirmation; 2. Aged 18 - 80, regardless of gender; 3. Agreed to undergo a lumbar puncture, with known status of cerebrospinal fluid and serum ? - free light chains (? - FLC), albumin, and oligoclonal bands (OCB); 4. Provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with peripheral nervous system disorders, infectious or neoplastic central nervous system diseases (monoclonal gammopathy or severe chronic kidney injury (GFR glomerular filtration rate <30 mL/min/1.73 m^2). 2. Patients with severe mental illnesses that prevent cooperation with tests or follow - up, and those who cannot or refuse to sign the informed consent form (or their legal representatives), are excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic performance of CSF ?-FLC-related indices and OCB; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic performance of cerebrospinal fluid ?-FLC-related indices and OCB; | — |
Countries
China
Contacts
Public ContactZhang Guoxun
Yan'an University Xianyang Hospital
Outcome results
None listed