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Validation and Process Optimization of Rapid Screening Tools for Geriatric Upper Gastrointestinal Bleeding

Clinical Validation and Rapid Screening Process Optimization of Risk Assessment Tools for Geriatric Upper Gastrointestinal Bleeding

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110199
Enrollment
Unknown
Registered
2025-10-10
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric Upper Gastrointestinal Bleeding

Interventions

Endoscopic Intervention Group:None
Control group:None

Sponsors

Beijing Friendship Hospital Pinggu Campus,Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age >=65 years; 2. Confirmed diagnosis of upper gastrointestinal bleeding (UGIB), meeting at least one of the following: - Hematemesis or coffee-ground emesis (blood oxidized by gastric acid); - Melena or hematochezia (after excluding dietary/drug interference, e.g., iron/bismuth supplements); - Gastric tube aspiration of bright red/coffee-ground fluid; - Hemoglobin drop >=20g/L from baseline with exclusion of bleeding from other sites. 3. Completion of non-contrast CT and laboratory tests (lactate, BUN/Cr ratio, etc.) within 24 hours of hospital admission.

Exclusion criteria

Exclusion criteria: 1. Missing/incomplete endoscopic data (e.g., undocumented bleeding source or severity); 2. Non-UGIB sources of bleeding: - Definite lower gastrointestinal bleeding (originating distal to Treitz ligament); - Traumatic bleeding (e.g., post-intubation mucosal injury). 3. End-stage diseases interfering with prognosis assessment: - Advanced malignancy (life expectancy <3 months); - End-stage heart/liver/renal failure (requiring dialysis or ICU support). 4. Imaging confounders: - Recent (within 72 hours) contrast-enhanced CT/CTA (may mask bleeding signs); - Altered gastroduodenal anatomy (e.g., post-subtotal gastrectomy).

Design outcomes

Primary

MeasureTime frame
Endoscopic Intervention Need;

Secondary

MeasureTime frame
Rebleeding rate;Length of stay (LOS);Blood transfusion volume;ICU occupancy rate;30-day mortality rate;

Countries

China

Contacts

Public ContactXue Guan

Beijing Friendship Hospital Pinggu Campus,Capital Medical University

gx19950127@163.com+86 132 6139 3402

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026