Sciatica
Conditions
Interventions
Group A:Under ultrasound guidance, gluteus maximus injection (betamethasone 5 mg + normal saline 1 ml) + transforaminal epidural injection (normal saline 2 ml)
Group B:Transforaminal epidural injection (betamethasone 5 mg + normal saline 1 ml) + ultrasound-guided gluteus maximus injection (normal saline 2 ml)
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with sciatica, which is confirmed by magnetic resonance imaging (MRI) to be caused by lumbar intervertebral disc herniation compressing the sciatic nerve; 2. Aged between 18 and 70 years old; 3. The duration of symptoms is between 6 weeks and 12 months; 4. Ineffective after at least 6 weeks of conservative and non-invasive treatment; 5. The patient is willing and able to give consent, including but not limited to: drug treatment, physical therapy, and adjustment of daily activities.
Exclusion criteria
Exclusion criteria: 1. Severe neurological deficits (such as foot drop/cauda equina syndrome, etc.); 2. Previous spinal surgery for the same intervertebral disc (segment); 3. Sciatic nerve pain symptoms lasting for more than 12 months; 4. Age 70 years old; 5. Receiving any corticosteroid treatment within the last month before study enrollment; 6. Patients with any contraindications to the drugs involved in the study; 7. More than two symptomatic segments with unilateral imaging abnormalities; 8. Known pregnancy of the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oswestry Disability Index of low back; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores for lower limb and low back pain;EQ-5D-5L score;MacNab score; | — |
Countries
China
Contacts
Public ContactFangcai Li
The Second Affiliated Hospital Zhejiang University School of Medicine
Outcome results
None listed