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Clinical study on the correlation between brain region activity and disease severity in IBD patients

Clinical study on the correlation between brain region activity and disease severity in IBD patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110174
Enrollment
Unknown
Registered
2025-10-09
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel disease

Interventions

Control group:None

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: IBD group: 1. Age: 18-60 years old, male or female; 2. Meet the clinical diagnostic criteria for IBD, and confirm the diagnosis by endoscopy, histopathological and imaging evidence; 3. Diagnosed with IBD for at least 4 months; 4. Right-handed; 5. Educated for more than 9 years; 6. Native Chinese speaker. Control group: 1. Healthy volunteers with gender and age matching; 2. No history of digestive system diseases and neurological diseases; 3. Right-handed; 4. Educated for more than 9 years; 5. Native Chinese.

Exclusion criteria

Exclusion criteria: 1. History of neurological disease, mental illness, head trauma/metal implants; 2. Use of psychotropic drugs, glucocorticoids, antibiotics or other drugs that may affect cerebral hemodynamics within 6 months; 3. Color blindness or color weakness; 4. Pregnant and lactating women; 5. Serious other diseases at the same time, such as severe liver disease, cardiovascular disease, lung disease, kidney disease, malignant tumor.

Design outcomes

Primary

MeasureTime frame
deoxyhemoglobin(HbR);oxyhemoglobin(HbO2);

Secondary

MeasureTime frame
Task performance rating;

Countries

China

Contacts

Public ContactLan Li

The First Affiliated Hospital of Zhejiang University School of Medicine

doctorlilan@163.com+86 571 8723 6861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026