Postoperative pain after microvascular decompression surgery for hemifacial spasm or trigeminal neuralgia
Conditions
Interventions
Liposome bupivacaine group:Liposome bupivacaine local infiltration of the incision site
Sponsors
The Second Affiliated Hospital, College of Medicine Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 18 years old or above. 2. Patients with ASA classification = III and scheduled for craniotomy and microvascular decompression surgery.
Exclusion criteria
Exclusion criteria: 1. Trauma or emergency patients; 2. Patients with cardiac conduction block (such as sinus node conduction block or atrioventricular conduction block); 3. Patients with coagulation dysfunction; 4. Patients who have engaged in alcohol abuse or have a severe dependence on anesthetic drugs within the past 2 months; 5. Patients suffering from uncontrolled anxiety disorders, schizophrenia or other mental illnesses; 6. Patients with a history of allergy to local anesthetics or non-steroidal drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC NRS-R0-72; | — |
Secondary
| Measure | Time frame |
|---|---|
| The situation of emergency pain relief within 72 hours after the operation;The time required for the first postoperative analgesic administration within 72 hours after the operation;NRS scores at 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours after the operation;Hemodynamic data;Length of hospital stay and hospital expenses;QoR-15 score; | — |
Countries
China
Contacts
Public ContactYan Min
The Second Affiliated Hospital, College of Medicine Zhejiang University
Outcome results
None listed