Postoperative pulmonary complications
Conditions
Interventions
The control group (Fixed Tidal Volume group, FV group):The control group (fixed VT group, FV group) received a conventional protective ventilation strategy with a fixed tidal volume (VT) of 7 ml/kg pr
The experimental group (Individualized Tidal Volume group, IV group):The experimental group (individualized VT group, IV group) received an individualized tidal volume (VT) during one-lung ventilation
Sponsors
The People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients scheduled to undergo mechanical ventilation under endotracheal intubation and general anesthesia; 2. Planned for major non-cardiothoracic and non-neurosurgical procedures; 3. Anticipated surgical duration exceeding 2 hours; 4. Age greater than 40 years; 5. Either sex; 6. American Society of Anesthesiologists (ASA) physical status classification I–III.
Exclusion criteria
Exclusion criteria: 1. Severe pulmonary, hepatic, or renal insufficiency; 2. Severe infection; 3. Pregnancy; 4. Patient withdrew informed consent; 5. Actual ventilation time less than 2 hours; 6. Intraoperative blood loss exceeding 500 mL; 7. Surgery canceled; 8. Intraoperative severe hypotension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function indices;ICU admission rate and length of stay; | — |
Countries
China
Contacts
Public ContactYuan Rui
The People's Hospital of Ningxia Hui Autonomous Region
Outcome results
None listed