Postpartum sleep disorder
Conditions
Interventions
control group:Labor analgesia with 1mg/ml ropivacaine
Hydromorphone 0.015mg/ml group:Hydromorphone assisted epidural labor analgesia
Sponsors
Women's Hospital School of Medicine Zhejiang University
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Age 20~50 years old 2.BMI 18.5~30 3. American Society of Anesthesiologists (ASA) Class II 4. Women who are full-term (>=37 weeks old), singleton, spontaneous childbirth, and contraction pain (NRS>=3 points) who require epidural delivery analgesia. 5. None of the mothers had electrolyte disorders, infections, immunity, or severe endocrine system diseases.
Exclusion criteria
Exclusion criteria: The patients were complicated with mental disease, central nervous system disease, liver disease, renal dysfunction and cardiopulmonary dysfunction; Have sleep disorders (such as insomnia, sleep apnea, etc.); There were severe obstetric complications and complications such as preeclampsia and eclampsia, pregnancy induced hypertension, placenta previa, placental abruption; Stillbirth, stillbirth, neonatal malformation; There are contraindications to hydromorphone use (such as those allergic to hydromorphone and hydromorphone salt; those with respiratory depression; those with severe or acute bronchial asthma; and those at risk of gastrointestinal obstruction); Contraindications to spinal anesthesia; Abnormal coagulation function; Severe hypovolemia and hemodynamic instability; Taking anticoagulant drugs; Taking cardiovascular drugs, non steroidal anti-inflammatory drugs, hormone drugs, antipsychotic drugs, anti anxiety drugs, antidepressants with sedative effect, etc. in the near future; And the pregnant women who refused to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sleep disorders on the first day after delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| numerical rating scale;the score of pittsburgh sleep quality index;the score of Pain numerical rating scale; Anxiety ;Incidence of sleep disorders on the 2nd and 3rd day after delivery;Ramsay ;Insomnia severity;Depression; | — |
Countries
China
Contacts
Public ContactLili Xu
Women's Hospital School of Medicine Zhejiang University
Outcome results
None listed