Heart failure
Conditions
Interventions
A group:While administering recombinant human brain natriuretic peptide for heart failure treatment, a fluid intake restriction protocol is implemented: According to the 2018 Chinese Guidelines for th
B group:While administering recombinant human brain natriuretic peptide (rhBNP) for the treatment of heart failure, a liberal fluid management strategy is implemented. Upon enrollment, patients receiv
1000 mL of 10% glucose injection
Sponsors
Ordos Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Informed and signed the informed consent form, willing to actively cooperate with treatment. 2. Age between 18 and 80 years. 3. Echocardiography reveals left ventricular ejection fraction (LVEF) <=40%, along with manifestations such as left ventricular enlargement and increased left ventricular end-systolic volume. 4. New York Heart Association (NYHA) functional class II–IV. 5. Meets the diagnostic criteria for acute worsening of chronic heart failure as outlined in the *Chinese Expert Consensus on Comprehensive Management of Patients with Worsening Chronic Heart Failure (2022)*.
Exclusion criteria
Exclusion criteria: 1. Presence of malignancy, severe neuroendocrine disorders, or psychiatric disorders. 2. Existence of severe infectious diseases or concomitant severe hepatic or renal insufficiency. 3. Accompanied by severe language impairment or psychiatric illness. 4. Imaging findings revealing significant pleural effusion or ascites.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Rehospitalization rate ;Living quality;Hospitalization expenses;Fatality rate;The duration of hospital stay; | — |
Primary
| Measure | Time frame |
|---|---|
| The level of N-terminal pro-brain natriuretic peptide (NT-proBNP);The severity of blood stasis symptoms;The severity of thirst symptoms; | — |
Countries
China
Contacts
Public ContactLiu Xi
Ordos Central Hospital
Outcome results
None listed