Pain perception in healthy individuals
Conditions
Interventions
Interventional group 1:First, transcranial ultrasound real stimulation, followed by transcranial ultrasound sham stimulation.
Interventional group 2:First, transcranial ultrasound sham stimulation, followed by transcranial ultrasound real stimulation.
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Healthy adult individuals aged over 18 years, right-handed; 2. No significant emotional fluctuations in the past week; 3. Normal cognitive function, able to understand the experimental procedure and actively cooperate with the study; 4. Normal vision, or corrected to normal vision; 5. Voluntarily participated in the study and provided written informed consent.
Exclusion criteria
Exclusion criteria: 1.Presence of conditions involving sensory abnormalities; 2.Presence of significant skin damage or skin diseases (affecting sensory testing); 3.Presence of neurological or psychiatric disorders (such as depression, anxiety, bipolar disorder, schizophrenia, etc.); 4.Presence of a history of head trauma or significant organic brain lesions (such as brain tumors, cerebral infarction, etc.); 5.Presence of diseases of other systems that may affect brain function (such as cardiovascular diseases, metabolic disorders, hematological diseases, infectious diseases, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heat pain threshold;Pressure pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse event;Event-related potentials during repetitive pulsed heat stimulation task;The positive and negative affect;Self-report emotional state; | — |
Countries
China
Contacts
Public ContactJie Jia
Huashan Hospital, Fudan University
Outcome results
None listed