Meningioma
Conditions
Interventions
Liposomal Bupivacaine Group:Made SNB with liposomal bupivacaine.
Ropivacaine Group:Made SNB with ropivacaine.
Placebo Group:Made SNB with Normal saline.
Sponsors
The First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in and cooperate with this experimental study; 2. between the ages of 20 and 60 inclusive, having completed at least elementary education; 3.Body mass index (BMI) between 18 kg/m^2 and 28 kg/m^2 inclusive; 4.ASA physical status classification of I or II; 5.Elective craniotomy for definitive resection of a primary meningioma; 6.Surgical incision in the frontal, temporal, parietal, or occipital areas; 7.The surgery lasted 4 to 6 hours.
Exclusion criteria
Exclusion criteria: 1.People accepting ore than twice craniocerebral surgeries; 2.Combining with severe systemic disease; 3.With scalp nerve block contraindicated; 4.A history of opioid or psychotropic addiction; 5.Needing blood transfusion; 6.People not taking part in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The score of Quality of Recovery-15;The score of Mini-mental State Examination;Visual Analog Scale,VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| S100ß calcium binding protein ß,S100ß;Neuron-Specific Enolase,NSE;Interleukin-6,IL-6;Tumor Necrosis Factor-a,TNF-a; | — |
Countries
China
Contacts
Public ContactYuxin Wang
The First Affiliated Hospital of Kunming Medical University
Outcome results
None listed