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Preoperative pain sensitivity score guides intraoperative analgesic drug use and its association with postoperative acute pain:A single-center, double-blind, randomized controlled trial

Preoperative pain sensitivity score guides intraoperative analgesic drug use and its association with postoperative acute pain:A single-center, double-blind, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110102
Enrollment
Unknown
Registered
2025-09-30
Start date
2025-05-07
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological cancer

Interventions

Control group (low pain sensitivity):The induced concentration of sufentanil is 0.3µg/kg
Control group (high pain sensitivity):The induced concentration of sufentanil is 0.3µg/kg
Intervention group (high pain sensitivity):The induced concentration of sufentanil is 0.4µg/kg
Intervention group (low pain sensitivity):The induced concentration of sufentanil is 0.2µg/kg

Sponsors

Shengjing Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) classification I-II; 2. Age >= 18 years and >= 75 years; 3. Planned for laparoscopic total hysterectomy, vaginal total hysterectomy, or open abdominal total hysterectomy; 4. Patient and their family have provided consent and signed the informed consent form; 5. No allergy to opioids.

Exclusion criteria

Exclusion criteria: 1.Complicated with serious diseases of liver, brain, heart, kidney, lung and hematopoietic system; 2.History of anxiety and depression, history of psychiatric diseases; 3.A history of drug or alcohol addiction; 4.Allergic constitution; 5.The patient refused.

Design outcomes

Primary

MeasureTime frame
Pain level;Postoperative 24-hour PCIA consumption (mL);Demand for Clamping Analgesia Pumps (Number of People);Occurrence of adverse reactions;

Countries

China

Contacts

Public ContactGuang Han

Shengjing Hospital Affiliated to China Medical University

cmu_hg@163.com+86 18940258839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026