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Single-cell sequencing study of carotid body tumors

Clinical research protocol for single-cell sequencing of carotid body tumors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110084
Enrollment
Unknown
Registered
2025-09-30
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid body tumor

Interventions

CBT group:NA
Control group:NA

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: CBT group: Diagnosed as primary CBT by imaging (DSA/CTA/MRI) and pathology, with Shamblin classification of type I-III; aged 18-70 years, gender not limited; no radiotherapy, chemotherapy or targeted therapy received; had the ability to give informed consent and signed the informed consent form; Control group: Diagnosed as carotid artery stenosis (stenosis rate >= 70%) by ultrasound or CTA; age and gender matched with the CBT group (+/-5 years); required carotid endarterectomy (CEA) and could obtain normal carotid body specimens during the operation; no history of CBT or other tumor diseases.

Exclusion criteria

Exclusion criteria: CBT group: Diagnosed as primary CBT by imaging (DSA/CTA/MRI) and pathology, with Shamblin classification of types I-III; aged 18-70 years, gender not limited; had not received radiotherapy, chemotherapy or targeted therapy; had the ability to give informed consent and signed the informed consent form.

Design outcomes

Primary

MeasureTime frame
Single-cell transcriptome of carotid body/carotid body tumor;

Countries

China

Contacts

Public ContactHu Huanrui

West China Hospital, Sichuan University

huhuanrui@126.com+86 180 4874 4930

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026