Carotid body tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: CBT group: Diagnosed as primary CBT by imaging (DSA/CTA/MRI) and pathology, with Shamblin classification of type I-III; aged 18-70 years, gender not limited; no radiotherapy, chemotherapy or targeted therapy received; had the ability to give informed consent and signed the informed consent form; Control group: Diagnosed as carotid artery stenosis (stenosis rate >= 70%) by ultrasound or CTA; age and gender matched with the CBT group (+/-5 years); required carotid endarterectomy (CEA) and could obtain normal carotid body specimens during the operation; no history of CBT or other tumor diseases.
Exclusion criteria
Exclusion criteria: CBT group: Diagnosed as primary CBT by imaging (DSA/CTA/MRI) and pathology, with Shamblin classification of types I-III; aged 18-70 years, gender not limited; had not received radiotherapy, chemotherapy or targeted therapy; had the ability to give informed consent and signed the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single-cell transcriptome of carotid body/carotid body tumor; | — |
Countries
China
Contacts
West China Hospital, Sichuan University