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A study on the Effects of Oxelidine on Catheter-related bladder Irritation Syndrome and Sleep Quality after Surgery

A study on the Effects of Oxelidine on Catheter-related bladder Irritation Syndrome and Sleep Quality after Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110055
Enrollment
Unknown
Registered
2025-09-29
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheter-Related Bladder Discomfort (CRBD)

Interventions

Control group:At the end of the operation, an equal volume of 1ml of normal saline was injected as a blank control, and other anesthesia management was the same
Oliceridine group:At the end of the operation, oxelidine was administered intravenously (the recommended dosage is based on the instructions and previous experience, 1mg) in a single dose

Sponsors

The Navy Specialized Medical Center of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=18 years old; 2.ASA classification I - III; 3. Undergo elective surgeries related to the urinary system under general anesthesia, and have a urinary catheter indwelled after the operation. 4. After the operation, you can communicate and cooperate with the medical team. 5. Those who have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergic to oxelidine or other opioid drugs; 2. Preoperative patients have difficulty in urination, bladder nerve regulation disorders, or severe urinary tract infections; 3. There are severe disorders of heart, lung, liver and kidney functions; 4. Those with cognitive dysfunction, language communication disorders or mental illnesses that affect the accuracy of the score; 5. Pregnant or lactating women; 6. History of opioid resistance, drug abuse or dependence; 7. Those who refuse to participate in the research or withdraw halfway.

Design outcomes

Primary

MeasureTime frame
Catheter-Related Bladder Discomfort (CRBD)csore;

Secondary

MeasureTime frame
Sleep quality score (RCSQ);

Countries

China

Contacts

Public ContactChen Wang

The Navy Specialized Medical Center of the People's Liberation Army of China

547359253@qq.com+86 191 1733 9371

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026