Mechanism and diagnostic value of miR-3942-5p in placenta-derived plasma exosomes in spontaneous preterm labor

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500110046

Enrollment

Unknown

Registered

2025-09-29

Start date

2024-10-21

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous preterm birth in first trimester pregnant women

Interventions

Gold Standard:Ultrasonic measurement of cervical length and morphology and determination of fetal fibronectin (fFN)

Index test:The expression level of miR-3942-5p in placenta-derived plasma exosomes was detected by Q-PCR

Eligibility

Sex/Gender

Female

Age

20 Years to 34 Years

Inclusion criteria

Inclusion criteria: 1. Primiparous pregnant women aged 20–35 years; 2. Gestational age of 28 to 31+6 weeks; 3. Spontaneous preterm labor.

Exclusion criteria

Exclusion criteria: 1. Multiple gestation; 2. The enrolled subjects have received treatment for related diseases, a history of hypertension, significant illnesses or family history thereof, or malnutrition.

Design outcomes

Primary

Measure	Time frame
miR-3942-5p in placenta-derived plasma exosomes;Diagnostic accuracy of EXOPD hsa-miR-3942-5p for spontaneous preterm birth;	—

Countries

China

Contacts

Public ContactGeng Mengyuan

Tianjin Central Hospital of Gynecology Obstetrics

gmy0309@126.com+86 22 58287405

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026