Irreversible pulpitis and apical periodontitis
Conditions
Interventions
Experimental Group:Underwent pulp regeneration therapy using concentrated growth factor (CGF)
Control Group:Underwent pulp regeneration therapy using blood clot
Sponsors
Air Force Medical Center
Eligibility
Sex/Gender
All
Age
9 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. According to the latest national teaching materials for colleges and universities, "Cariology and Endodontics, Fifth Edition", edited by Zhou Xuedong, People's Medical Publishing House, 2020 "and" the Guideline of root canal Treatment Technique "published in Chinese Journal of Stomatology by Society of Cariology and Endodontics, Chinese Stomatological Association in 2014, the inclusion criteria were set as the age of 9-45 years old. 2. Diagnosis of irreversible pulpitis or pulp necrosis or periapical periodontitis; 3. The X-ray films showed that there was no filling material in the root canal, the apical foramen was developed and closed, the periapical space was normal, the periapical membrane cavity was widened, or the apical low density shadow (the shadow diameter was less than 5mm). 4. Patients agreed to participate in the trial and provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe systemic diseases or pregnant women; 2. Cracked tooth, crown fracture or root fracture; 3. Internal or external root resorption; 4. The presence of opposing teeth; 5. No adjacent teeth contact; 6. Root canal curvature greater than 45 degrees; 6. Chronic periodontal disease, periodontal purulent discharge, abnormal root loosening; 7. The root canal cannot be effectively dredged to the root tip; 8. Presence of root canal perforation or separation of root canal instruments; 9. The large area defect of the affected tooth could not be repaired in the later period. 10. Severe calcification or atresia of the root canal.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Pain index 1 week after surgery;Electric Pulp Test (EPT);Degree of vascular ingrowth in the root canal; | — |
Primary
| Measure | Time frame |
|---|---|
| One year success rate after surgery; | — |
Countries
China
Contacts
Public ContactHe Wenxi
Department of Stomatology, Air Force Medical Center
Outcome results
None listed