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Effect of submucosal injection of different concentrations of epinephrine on adverse effects after EMR in colorectal polyps

Effect of submucosal injection of different concentrations of epinephrine on adverse effects after EMR in colorectal polyps

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110027
Enrollment
Unknown
Registered
2025-09-29
Start date
2025-06-04
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyp

Interventions

A Group:Intraoperative submucosal injection of high concentrations of epinephrine in EMR.
B Group:Intraoperative submucosal injection of low concentrations of epinephrine in EMR.

Sponsors

Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 18~80 years old, male or female; 2. Colorectal polyps that meet the indications for endoscopic intestinal EMR resection and have a diameter of >=10mm and a <=20mm; 3. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Peculated polyps; 2. Known hypersensitivity to epinephrine; 3. Patients with abnormal coagulation function or taking aspirin; 4. Those with other heart, liver and kidney diseases who are unable to undergo intestinal EMR surgery; 5. Refusal to undergo colorectal polyp resection due to personal reasons.

Design outcomes

Primary

MeasureTime frame
Post-procedural bleeding rate;—

Secondary

MeasureTime frame
Postoperative abdominal pain rate and pain scores;Postoperative perforation rate;Surgical Costs;Surgical time;—

Countries

China

Contacts

Public ContactLisheng Wang

Shenzhen People's Hospital

wanglsszrmyy@163.com+86 137 1472 5662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026