Postoperative Behavioral and Emotional Abnormalities
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 1-3 years; 2.ASA physical status I-II; 3.Scheduled for elective fundus examination under general anesthesia 4.Written informed consent obtained from parents/legal guardians
Exclusion criteria
Exclusion criteria: 1.History of neurological or psychiatric disorders; 2.Comorbid oral or gastrointestinal diseases, or immune-related disorders; 3.Antibiotic or probiotic use within 1 month prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral microbial indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Child Behavioral Assessment;emergency delirium;Negative postoperative behavioral changes;Basic characteristics of children before surgery;Medical history of children before surgery;History of general anesthesia in children before surgery;Feeding history;Birth history; | — |
Countries
China
Contacts
Peking University People's Hospital