Hemifacial spasm
Conditions
Interventions
Intervention group:Based on the experimental spasm recognition model, when the TENG sensor detects facial muscle spasms, it initiates closed-loop electrical stimulation of the facial nerve.
Healthy control group:No
Sponsors
Tsinghua University Yuquan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 70 years (inclusive); 2. No restrictions on gender; 3. Diagnosis of moderate to severe primary hemifacial spasm (HFS), with a disease duration of at least 6 months and clinically stable symptoms; 4. Prior inadequate response to botulinum toxin injections, or patient refusal/intolerance to repeated injections, or contraindication/unwillingness to undergo microvascular decompression surgery; 5. Ability to comprehend the study procedures and provide voluntary informed consent; 6. Absence of implanted electronic medical devices (e.g., cardiac pacemakers), with intact facial skin and no open wounds or active infections; 7. Capacity to comply with the use of electro-stimulation glasses and complete all scheduled follow-up assessments.
Exclusion criteria
Exclusion criteria: 1. Refusal to sign the informed consent form or poor compliance; 2. Secondary hemifacial spasm (such as due to tumors, brainstem vascular lesions, etc.) or coexisting with other neurological disorders (such as epilepsy, Parkinson's disease, post-stroke sequelae, etc.); 3. Having participated in other interventional clinical trials within the recent 90 days (before the start of the study); 4. Having undergone facial nerve surgery or having any facial electrical stimulation device implanted; 5. Presence of severe dermatitis, infection, ulceration or skin lesions on the face that are not suitable for electrode placement; 6. Comorbid with severe cardiovascular disorders (such as recent myocardial infarction, refractory arrhythmia) or having an implanted cardiac electronic device; 7. Suffering from severe mental disorders (severe depression, schizophrenia, etc.) or cognitive dysfunction, unable to complete objective assessment; 8. Pregnant women or breastfeeding women, or planning to get pregnant during the study period; 9. Other situations that the researchers consider unsuitable for participating in this study (such as severe visual impairment affecting video assessment, inability to tolerate electrical stimulation, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial Skin Movement Signals ;Facial Electromyography (EMG) Data ;Video surveillance footage;Eye-tracking data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Self-Assessment Scale; | — |
Countries
China
Contacts
Public ContactJinting Wu
Tsinghua University Yuquan Hospital
Outcome results
None listed