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Dexmedetomidine Nasal Drops Combined with Sevoflurane Inhalation for Sedation in Pediatric Patients Undergoing Single-Region MRI: A Retrospective Study

Dexmedetomidine Nasal Drops Combined with Sevoflurane Inhalation for Sedation in Pediatric Patients Undergoing Single-Region MRI: A Retrospective Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110007
Enrollment
Unknown
Registered
2025-09-28
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Patients Undergoing Single-Region MRI

Interventions

Observation group (Dexmedetomidine nasal drops combined with sevoflurane inhalation):None

Sponsors

Children's Hospital Affiliated to Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 12 Years

Inclusion criteria

Inclusion criteria: (1) American Society of Anesthesiologists (ASA) physical status classification I - II; (2) MRI examination of a single site.

Exclusion criteria

Exclusion criteria: (1) Acute respiratory tract infection or asthma attack within the past 2 weeks; (2) Body temperature exceeding 38.5°C; (3) Severe impairment of liver or kidney function; (4) Primary disease accompanied by pain; (5) History of allergy to dexmedetomidine or sevoflurane; (6) Use of other sedative-hypnotic drugs within the past 24 hours.

Design outcomes

Primary

MeasureTime frame
Success rate of the examination;

Secondary

MeasureTime frame
The MOAA/S score of the child every 5 minutes after dexmedetomidine nasal administration;MRI examination time;Sedation time and recovery time;Vital signs at each time point;Adverse reactions during the sedation process;

Countries

China

Contacts

Public ContactKong Xiangyi

Children's Hospital Affiliated to Shandong University

532757434@qq.com+86 181 4314 7205

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026