Chronic obstructive pulmonary disease and cardiovascular disease
Conditions
Interventions
Intervention group 1:Conduct a 12-week inspiratory muscle training program at 30%–60% MIP using a decremental flow-resistive breathing trainer, elliptical machine, stationary bike, and shoulder press/
Intervention group 2:Conduct a 12-week inspiratory muscle training program at 30%–60% MIP, combined with aerobic (Western-style) and resistance training using an elliptical machine, stationary bike, a
Intervention group 3:Conduct a 12-week inspiratory muscle training program at 30%–60% MIP, combined with Chinese-style aerobic training and resistance training using an elliptical machine, stationary
Intervention group 4:Conduct a 12-week inspiratory muscle training program at 30%–60% MIP, combined with Chinese-style aerobic training (with remote monitoring) and resistance training using an ellipt
Sponsors
West China School of Public Health and West China Fourth Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. According to the American Thoracic Association (ATS)/Respiratory ERS standards, patients with FEV1/FVC= 1400mm/s; 4. Agree to participate in this experiment and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Has undergone pulmonary resection or lobectomy within the past 6 months; 2. Having pneumothorax or rib fractures; 3. Severe movement disorders (not caused by chronic obstructive pulmonary disease), or other neurological, muscular, skeletal, or cardiovascular diseases that seriously affect the safety of the subject's training; 4. Severe heart disease (acute heart failure or myocardial infarction, unstable angina, uncontrolled arrhythmia, third degree atrioventricular block patients, unexplained chest pain and palpitations); 5. Pregnancy or breastfeeding; 6. Individuals with cognitive impairment or other inability to cooperate with training; 7. Individuals who have not signed informed consent forms; 8. Participate in other similar experiments; 9. Strict inclusion and exclusion criteria will be applied to exclude subjects with a pulmonary bulla diameter greater than 1cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of arteriosclerosis;Pulmonary function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lifestyle;Blood pressure;Blood fat;Blood sugar;Anthropometric measurements;Handgrip strength;Body composition;Electrocardiography (ECG);Carotid ultrasonography;6-minute walk test;Bone mineral density;Liver fibrosis measurement;Muscle strength test; | — |
Countries
China
Contacts
Public ContactYang Shujuan
West Fourth Hospital, Sichuan University / West China School of Public Health
Outcome results
None listed