Oral squamous cell carcinoma
Conditions
Interventions
OSCC Group:None
Healthy Group:None
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Experimental Group: (1) Be 18 years of age or older; (2) No gender restrictions; (3) Treatment Stage: Patients diagnosed with oral squamous cell carcinoma who have not previously received or are currently undergoing radiotherapy and chemotherapy; (4) Diagnostic Group: Patients with a confirmed pathological diagnosis of oral squamous cell carcinoma; (5) Screening Group: High-risk population for oral squamous cell carcinoma, including: 1) Patients diagnosed with oral leukoplakia or erythroplasia; 2) Individuals with a family history or genetic predisposition to oral squamous cell carcinoma; 3) Patients with long-term exposure (10 years or more) to known carcinogens such as tobacco, alcohol, or betel nuts; 4) Patients with oral lesions highly suspicious of malignancy but not yet diagnosed. Healthy Control Group: (1) Be 18 years of age or older; (2) No gender restrictions; (3) No history or current diagnosis of oral squamous cell carcinoma.
Exclusion criteria
Exclusion criteria: (1) Patients with malignant tumors in other parts of the body; (2) Patients who have already participated in other clinical studies; (3) Patients with severe mental illness or cognitive impairment who are unable to understand and comply with the research requirements; (4) Patients who are undergoing drug treatment that may affect the research results (such as antibiotics and anti-inflammatory drugs) and are unable to stop taking the medication; (5) Patients with drug abuse or alcoholism that affects their compliance with the study; (6) Patients who are not suitable to participate in this study as stipulated by law or ethics; (7) Patients who the researcher deems unsuitable for inclusion in the study (such as those with other factors that may affect the study results).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral exhaled gas metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| saliva metagenomics; | — |
Countries
China
Contacts
Public ContactJiannan Liu
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed