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The effect of transcutaneous auricular vagus nerve stimulation on postoperative delirium in elderly patients undergoing major laparoscopic abdominal surgery

The effect of transcutaneous auricular vagus nerve stimulation on postoperative delirium in elderly patients undergoing major laparoscopic abdominal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109970
Enrollment
Unknown
Registered
2025-09-28
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

The percutaneous auricular vagus nerve stimulation group (taVNS) group:A commercial transcutaneous electrical nerve stimulation device (Roscoe TENS7000) was used for stimulation, with a custom stimula
Sham stimulation (SS) group:The stimulation was performed using the commercial transcutaneous electrical nerve stimulation device (Roscoe TENS7000), with two electrode clamps attached to the earlobe a

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Age 65 to 85 years old; 2.ASA grade II or III; 3.Communicate without obstacles and be willing to complete the neuropsychological test;

Exclusion criteria

Exclusion criteria: 1.Preoperative neuro-psychiatric disorders or long-term use of antidepressants or sedatives; 2.Impaired vision or hearing, making it impossible to conduct cognitive function assessment; 3.Those with sinus bradycardia and severe cardiopulmonary dysfunction before the operation; 4.The preoperative Mini-Mental State Examination (MMSE) score was less than 23 points; 5.Refuse to participate in this researcher; 6.Patients who were transferred to the ICU after the operation;

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative delirium;

Countries

China

Contacts

Public ContactHuanhuan Zhang

Hebei General Hospital

jiangxinyulu@163.com+86 311 8598 8127

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026