diabetes mellitus
Conditions
Interventions
High Vitamin D + High A/L Group:None
High Vitamin D + Low A/L Group:None
Low Vitamin D + High A/L Group:None
Low Vitamin D + Low A/L Group:None
Normal control Group:None
Sponsors
The People’s Hospital of Dazu, Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years, no gender restrictions; 2. Diagnosed with T2DM according to the diagnostic criteria established in the Chinese Diabetes Prevention and Treatment Guidelines (2024 Edition); 3. Complete laboratory and general medical records; 4. Willing to participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Other types of diabetes; 2. Acute diabetic complications such as diabetic ketoacidosis or hyperosmolar hyperglycemic state; 3. Diseases affecting bone metabolism, including hyperparathyroidism, hyperthyroidism, and rheumatoid arthritis; 4. Use of medications affecting bone metabolism within the past three months, such as vitamin D, calcium supplements, bisphosphonates, or glucocorticoids; 5. Severe systemic diseases such as serious infections, severe cardiac, hepatic, or renal impairment (heart failure, uremia, serum total bilirubin > 171 µmol/L, or direct bilirubin > 34 µmol/L; prothrombin activity 707 µmol/L, BUN > 28.6 mmol/L), severe water, electrolyte, and acid-base imbalances (e.g., serum potassium > 6.5 mmol/L, metabolic acidosis pH < 7.2), malignant tumors, etc.; 6. Patients with T2DM who have received insulin therapy within the past three months; 7. Women who are pregnant, breastfeeding, or taking long-term oral contraceptives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Plasma Glucose ,FPG;Fasting Insulin,FINS;Fasting C-Peptide,FCP;Glycated Hemoglobin,HbA1c;Triglyceride,TG; Total Cholesterol,TC;Low-Density Lipoprotein Cholesterol,LDL-C;High-Density Lipoprotein Cholesterol,HDL-C;25-Hydroxyvitamin D,25(OH)D;Adiponectin,ADPN;Leptin,LEP;Height;Weight;Blood Pressure,BP; | — |
Countries
China
Contacts
Public ContactChen Xiangfen
The People’s Hospital of Dazu, Chongqing
Outcome results
None listed