Attention Deficit/Hyperactivity Disorder
Conditions
Interventions
Precision Positioning-rTMS intervention Group:Calculate the functional connectivity between the PCC effector brain regions and IPL, and select the position with the largest functional connectivity as
Non-precise positioning-rTMS intervention group:The random coordinates of voxels located more than 10mm away from the precise positioning coordinates within the IPL mask are used as the stimulation ta
Standard drug treatment group:This group only take methylphenidate for treatment as a reference for rTMS therapeutic effect.
Baseline group :NA
Sponsors
The Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
8 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1. Age: 8 to 16 years old; 2. Meet the diagnostic criteria for attention deficit hyperactivity disorder (ADHD) in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) of the American Psychiatric Association; 3. No history of other mental disorders that affect cognitive function (such as intellectual disability) or organic brain diseases; 4. The IQ measured by the Wechsler Intelligence Scale for Children (WISC) is =80; 5. Obtain the written informed consent of the patient and their guardian.
Exclusion criteria
Exclusion criteria: 1. All contraindications for metal implants within the skull (such as cochlear implants, deep brain electrodes, etc.), pacemakers, intracardiac leads, etc., as well as all contraindications of magnetic resonance imaging scans, such as claustrophobia, etc. 2. Previous history of epilepsy: history of epileptic seizures, history of febrile convulsions in childhood; And those with epileptiform discharges shown on electroencephalogram; 3. Known brain injuries (such as tumors, stroke foci, etc.) or severe head trauma; 4. There has been a history of alcohol, drug or psychoactive substance abuse within the past six months; 5. Currently undergoing electroconvulsive therapy (ECT) or other nerve stimulation therapies (such as transcranial direct current stimulation (tDCS)); Those who have taken other psychotropic drugs within four weeks (except for methyl ester).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADHD symptoms scores ;inhibition control;sustained attention; | — |
Secondary
| Measure | Time frame |
|---|---|
| Behavioral problems and social adaptation levels ;social interaction;Adaptive Behavior Assessment ;Functional Impairment Rating;Executive Function ;attention assessment;working memory;cognitive flexibility;Brain function and neural networks; | — |
Countries
China
Contacts
Public ContactYufeng Zang
Hangzhou Normal University/ The Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed