Those with impaired airway clearance: presence of large amounts of sputum, mucus, and other secretions
Conditions
Interventions
Research group:Conventional therapy + OLE
Control group:conventional treatment
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 18 to 80 years of age; 2. Vital signs are stable. 3. Richmond Agitation-Sedation Score (RASS score) between -2 and +1; 4. Those with impaired airway clearance: presence of large amounts of sputum, mucus, and other secretions; ineffective or inefficient cough; presence of sputum sounds on auscultation, decreased ventilation or oxygenation; and chest CT/X-rays suggesting more inflammation of the lungs or pulmonary atelectasis. 5. The patients and their families were informed and consented to the study;
Exclusion criteria
Exclusion criteria: 1. Patients with atrial fibrillation, severe heart failure, haemodynamic instability; 2. Patients with active airway bleeding, severe emphysema, alveoli, history of pneumothorax within 3 months, total lung resection, pulmonary embolism; 3. Severe spinal and thoracic deformities, unhealed rib fractures; 4. Patients with pacemaker implants; 5. Pregnant and lactating women; 6. Patients with frequent vomiting within 1 week; 7. Other reasons why the medical team felt it was not appropriate to carry out the treatment; 8. Persons who have not signed the informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum colour and character, sputum viscosity, sputum volume;Clinical Pulmonary Infection Score;EIT parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough/expiratory peak flow rate;Tolerance level, safety;Blood gas analysis and oxygenation index;spirometry;Cost of antibiotic use;Semi-quantitative cough strength score;Maximum suction pressure, maximum exhalation pressure; | — |
Countries
China
Contacts
Public ContactHuang Tao
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed