stroke
Conditions
Interventions
Healthy control group:none
rTMS control group:The control group received routine upper limb rehabilitation treatment for 40 minutes each time. Upper limb rehabilitation training was carried out based on the motor function of st
Meanwhile, the control group received rTMS sham stimulation. The specific detailed parameters used for rTMS stimulation are as follows: stimulation frequency of 10Hz, stimulation intensity of 80% RMT,
Sponsors
Zhongda Hospital of Southeast University
Eligibility
Sex/Gender
All
Age
25 Years to 80 Years
Inclusion criteria
Inclusion criteria: Diagnostic criteria: Meet the diagnostic criteria for stroke in the 4th National Conference on Cerebrovascular Diseases, and diagnose ischemic stroke by auxiliary examination methods such as CT or MRI. Inclusion Criteria: 1. Age 25-80 years old (inclusive), male or female, clear consciousness, no severe cognitive impairment, able to complete the corresponding assessment in accordance with orders; 2. First unilateral stroke, the duration of cerebral infarction is less than or equal to 6 months (patients in the recovery period of stroke); 3. Stable clinical condition, with good control of underlying diseases such as coronary heart disease, hypertension, diabetes, and hyperlipidemia; 4. The stage of Brunnstrom hemiplegia of the upper extremities is stage II-IV; 5. All subjects are aware of the rules of this trial, agree to participate in this trial, and sign the informed consent form. Inclusion Criteria for Healthy Subjects: 1. Age 25~80 years old; 2. Good health, no cerebrovascular disease, no cranial and spinal cord injury, no neuromuscular disease or injury and other symptoms; 3. Agree to participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Progressive stroke or secondary cerebral hemorrhage; 2. Severe cognitive impairment or combined with multiple organ dysfunction; 3. Those who have abnormal upper limb function due to other diseases; 4. Use of unfractionated heparin or low molecular weight heparin in the past month; 5. History of tumor and surgery in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment-Upper Extremities; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index;resting motor threshold;Motor Evoked Potential;functional MRI ; | — |
Countries
China
Contacts
Public ContactPei Wang
Zhongda Hospital of Southeast University
Outcome results
None listed