Invasive mechanical ventilation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Endotracheal intubation or tracheostomy for >= 24 hours; 3. Successful passage of a spontaneous breathing trial (SBT); 4. Ability to cooperate with grip strength and ultrasound examinations; 5. Signed informed consent form obtained from the subject or their legally authorized representative.
Exclusion criteria
Exclusion criteria: 1.Pregnancy; 2. Massive pleural effusion, pneumothorax, or subdiaphragmatic infection; 3. Diaphragmatic paralysis; 4. Inability to obtain adequate ultrasound views of the chest or abdomen due to surgery or trauma; 5. Endotracheal intubation retained for >=21 days without a tracheostomy; 6. Patients for whom a decision to withdraw life-sustaining therapy has been made.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| grip strength;diaphragm thickness;diaphragm thickening fraction;diaphragm excursion; | — |
Secondary
| Measure | Time frame |
|---|---|
| diaphragm tissue doppler; | — |
Countries
China
Contacts
Shanghai Hebin Rehabilitation Hospital