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Safety and Efficacy of Pure Cut Followed by Targeted Vessel Coagulation and Clip Closure Versus Blended Electrocautery with Clip Closure in Endoscopic Mucosal Resection of Colorectal Polyps >=1 cm: A Prospective, Multicenter, Randomized, Single-blind Controlled Trial

Safety and Efficacy of Pure Cut Followed by Targeted Vessel Coagulation and Clip Closure Versus Blended Electrocautery with Clip Closure in Endoscopic Mucosal Resection of Colorectal Polyps>=1 cm: A Prospective, Multicenter, Randomized, Single-blind Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109917
Enrollment
Unknown
Registered
2025-09-26
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Polyps

Interventions

Pure Cut with Vessel Coagulation Group:Pure Cut with Vessel Coagulation
Conventional Blended Current Group:Conventional Blended Current

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Presence of one or more colorectal polyps, with a diameter of >=1 cm and <2 cm (including sessile, flat, or pedunculated morphologies), as confirmed by colonoscopy. 2.Age between 18 and 80 years, irrespective of gender. 3.Hospitalization at one of the 11 participating research centers and meeting all the eligibility criteria of this study. 4.Voluntary participation and provision of written informed consent.

Exclusion criteria

Exclusion criteria: 1.Current use of anticoagulants (e.g., warfarin, dabigatran, rivaroxaban) or antiplatelet agents (e.g., aspirin, clopidogrel) with a washout period of less than 7 days prior to the procedure. 2.Known history of hematologic diseases (e.g., hemophilia, leukemia) or laboratory-confirmed coagulation disorders. 3.Presence of severe cognitive impairment or psychiatric conditions that would preclude compliance with the endoscopic procedure or post-operative follow-up. 4.Unwillingness to provide written informed consent for the study.

Design outcomes

Primary

MeasureTime frame
Whether rebleeding has occurred;The time at which rebleeding occurred;Repeat endoscopy for bleeding;Delayed Post-Polypectomy Bleeding;

Secondary

MeasureTime frame
Procedure-Related Perforation Rate;Intraoperative Bleeding;

Countries

China

Contacts

Public ContactTao Zhang

Nanchong Central Hospital

305514271@qq.com+86 182 2731 2096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026