Heart failure
Conditions
Interventions
Gold Standard:Heart failure diagnosis is usually a combined diagnosis.
Clinical symptoms/signs: dyspnea, fatigue, edema, etc.
Echocardiogram: evidence of reduced left ventricular ejection fraction or
Index test:1. 6-minute walk test
2. Multi-omics sequencing such as transcriptome sequencing and proteome sequencing
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old; 2.Age <= 80years old; 3.Meet the diagnosis criteria for heart failure in the latest international and domestic authoritative guidelines; 4.Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Age 80 years old; 2.Patients with severe abnormal liver or kidney function, malignant tumors, or severe infections; 3.Patients from whom valid blood samples cannot be collected or those whom the researcher deems unfit to participate in the study; 4.Pregnant and lactating women; 5.Individuals without legal capacity or with limited legal capacity, or any situations that the researcher deems unfit for participation in this clinical study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause death;composite event endpoint;short-term non-relief of symptoms;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular death;progression of heart failure; | — |
Countries
China
Contacts
Public ContactJunnan Tang
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed