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A prospective, single-center, randomized control led study of laparoscopic single-port surgery system versus traditional laparoscopic surgery in radical proximal gastric cancer

A prospective, single-center, randomized control led study of laparoscopic single-port surgery system versus traditional laparoscopic surgery in radical proximal gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109905
Enrollment
Unknown
Registered
2025-09-26
Start date
2025-10-16
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Intervention group:All patients underwent domestic single-port robot-assisted proximal gastrectomy
Control group:Conventional laparoscopic proximal gastrectomy was performed

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-75 years old, ECOG score <=2; 2.Proximal gastric cancer or Siewert type II adenocarcinoma of esophagogastric junction, ct1-T3, N0-N +, M0, tumor diameter =4 cm, esophageal invasion <=2 cm; 3.Patients who plan to undergo Proximal Gastrectomy, have the anatomical basis of preserving the distal stomach, and can perform R0 resection and functional anastomosis during operation; 4. All cases were considered to be suitable for PG after MDT evaluation (but not necessary for total gastrectomy), and no neoadjuvant therapy was needed. 5. Imaging staging supported localized disease: enhanced CT or upper abdominal MRI showed no distant metastasis (liver, lung, peritoneum, etc.); 6.ASA anesthesia grade <=III, expected to tolerate surgery; 7. Liver, kidney, heart and lung function were good, blood routine and coagulation function were basically normal (preoperative test); 8. Signed the written informed consent, volunteered to participate in this study, and had good compliance; 9. The follow-up plan for at least 12 months after surgery can be completed.

Exclusion criteria

Exclusion criteria: 1.T3 or distant metastasis; 2. Esophageal infiltration >2 cm; 3. Previous subtotal or total gastrectomy; 4.Combined with other malignant tumors (within the past 5 years); 5. Patients with severe organic diseases who cannot tolerate anesthesia or surgery (such as severe heart failure, pulmonary fibrosis, etc.); 6. Emergency surgery for active gastric bleeding, perforation, acute obstruction, etc. 7. Pregnant or lactating women; 8. Patients with severe mental illness or cognitive impairment, unable to cooperate with the study process; 9. Patients deemed unsuitable for enrollment by the surgeon.

Design outcomes

Primary

MeasureTime frame
Complications;

Countries

China

Contacts

Public ContactXian Shen

The First Affiliated Hospital of Wenzhou Medical University

shenxian1120@126.com+86 139 6888 8872

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026