depression
Conditions
Interventions
Experimental group :Patients were treated with three iTBS treatments per day (1800 pulses, 50 minutes apart, stimulation intensity determined according to the patients tolerance, but not more than 120
Control group:Participants maintained a stable antidepressant medication regimen during the trial.
Sponsors
The Third People's Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Age
13 Years to 19 Years
Inclusion criteria
Inclusion criteria: 1. Patients who met the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (5 th) (DSM-5) for both depressive episodes and non-suicidal self-injurious; 2. Age 13-19 years; 3. Baseline Hamilton Depression Scale-17 scores are >=17; 4. Patients and his/her parent voluntarily participated in the study, understood and signed a written informed consent; 5.Participants maintained a stable antidepressant medication regimen during the trial.
Exclusion criteria
Exclusion criteria: 1. Patients with previous mental retardation, schizophrenia, compulsive disorder, bipolar disorder, or any other mental disorder are excluded; 2. depressive episodes secondary to other mental or physical disorders; 3. severe or unstable cardiac, liver, kidney, endocrine(thyroid diseases), blood, autoimmune diseases; 4. Women during lactation, pregnancy, or may become pregnant during the trial; 5. Previous or current alcohol dependence, significant substance abuse / dependence; 6. Those who have previously failed TMS, did not respond to ECT, or have a history of systemic psychotherapy; 7. Those who currently have contraindications to TMS, such as epilepsy or other organic brain sexual disease patients, newly implanted heart stents, metal dentures, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese Revised Ottawa Self-Injury Scale;17-item Hamilton Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton anxiety scale; | — |
Countries
China
Contacts
Public ContactJiang Lizhu / Cao Fang
The Third People's Hospital of Yunnan Province
Outcome results
None listed