Laparoscopic surgery, Children
Conditions
Interventions
Oxycodone group:Postoperative analgesic formula: oxycodone 50mg ? normal saline 100ml, loading dose 0.1mg/kg, bolus dose 0.05mg/kg, locked interval 15min (no background dose)
Sufentanil group:Postoperative analgesia formula: sufentanil 50ug ? normal saline 100ml, loading dose 0.1µg/kg, bolus dose 0.05µg/kg, locked interval 15min (no background dose).
Sponsors
Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: The age ranged from 6 to 12 years. American Society of Anesthesiologists (ASA) grade ?-?; Children undergoing laparoscopic major abdominal surgery (operation duration >2 hours) under general anesthesia; BMI 18-24 kg/m^2. Informed consent was obtained from the children's guardians.
Exclusion criteria
Exclusion criteria: Age 12 years old; The patient had a history of allergy to the test drugs. Severe systemic diseases, such as severe liver and kidney dysfunction; Recent history of analgesic use, drug abuse, or chronic pain; Impaired language communication; The child and his guardian declined to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The FLACC score at 24h after operation was recorded; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative FLACC score;Otal dose of PCIA administered 48h after surgery;Effective number of compressions;Rescue analgesia;Satisfaction of family members;Postoperative adverse reactions;Length of PACU stay; | — |
Countries
China
Contacts
Public ContactZhang Feng
Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed