primary acquired nasolacrimal duct obstruction
Conditions
Interventions
Observation group:none
Control group:none
Sponsors
Wuhu Eye Hospital
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Menopause: (1) Absence of menstruation for >=1 year; (2) Age >=45 years with a history of hysterectomy >=6 months prior; (3) Age >=45 years with bilateral oophorectomy >=6 months prior and serum follicle-stimulating hormone (FSH) level >40 mIU/mL. Meeting any one of the above criteria qualifies as meeting the menopausal standard. Experimental Group Inclusion Criteria: (1) Meeting the menopausal standard; (2) Meeting the diagnostic criteria for primary acquired nasolacrimal duct obstruction. Control Group Inclusion Criteria: (1) Meeting the menopausal standard; (2) Lacrimal irrigation: patent, with irrigation fluid fully entering the pharynx without reflux; (3) Absence of epiphora symptoms.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the experimental group: (1) Failure to meet the diagnostic criteria for menopause; (2) History of ocular inflammation other than dacryocystitis; (3) Ocular trauma history, chemical injuries to the cornea or conjunctiva, abnormal eyelid position, or any ocular disease other than refractive errors and age-related cataracts; (4) Diabetes mellitus or immune disorders affecting lacrimal secretion function, such as Sjögren's syndrome; (5) Long-term use of systemic medications that may exacerbate or induce dry eye, including hypnotics and anxiolytics. Exclusion criteria: (1) Failure to meet the diagnostic criteria for menopause; (2) Any ocular disease history or ocular trauma history other than age-related cataracts and refractive errors; (3) Diabetes mellitus or immune disorders affecting lacrimal secretion function, such as Sjögren's syndrome; (4) Long-term use of systemic medications that may exacerbate or induce dry eye, including hypnotics and anxiolytics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular surface parameter;Meibomian gland parameters;Tear cytokines; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic characteristics, severity of lacrimal duct obstruction, and history of dacryocystitis; | — |
Countries
China
Contacts
Public ContactJin Haili
Wuhu Eye Hospital
Outcome results
None listed